Students are introduced to the circulatory system, the heart, and blood flow in the human body. Through guided pre-reading, during-reading and post-reading activities, students learn about the circulatory system's parts, functions and disorders, as well as engineering medical solutions. By cultivating literacy practices as presented in this lesson, students can improve their scientific and technological literacy.

Students are introduced to the challenge question, which revolves around proving that a cabinet x-ray system can produce bone mineral density images. Students work independently to generate ideas from the questions provided, then share with partners and then with the class as part of the Multiple Perspectives phase of this unit. Then, as part of the associated activity, students explore multiple websites to gather information about bone mineral density and answer worksheet questions, followed by a quiz on the material covered in the articles.

Students learn about the role engineers and engineering play in repairing severe bone fractures. They acquire knowledge about the design and development of implant rods, pins, plates, screws and bone grafts. They learn about materials science, biocompatibility and minimally-invasive surgery.

Students examine an image produced by a cabinet x-ray system to determine if it is a quality bone mineral density image. They write in their journals about what they need to know to be able to make this judgment. Students learn about what bone mineral density is, how a BMD image can be obtained, and how it is related to the x-ray field. Students examine the process used to obtain a BMD image and how this process is related to mathematics, primarily through logarithmic functions. They study the relationship between logarithms and exponents, the properties of logarithms, common and natural logarithms, solving exponential equations and Beer's law.

Students investigate the bone structure of a turkey femur and then create their own prototype versions as if they are biomedical engineers designing bone transplants for a bird. The challenge is to mimic the size, shape, structure, mass and density of the real bone. Students begin by watching a TED Talk about printing a human kidney and reading a news article about 3D printing a replacement bone for an eagle. Then teams gather data—using calipers to get the exact turkey femur measurements—and determine the bone’s mass and density. They make to-scale sketches of the bone and then use modeling clay, plastic drinking straws and pipe cleaners to create 3D prototypes of the bone. Next, groups each cut and measure a turkey femur cross-section, which they draw in CAD software and then print on a 3D printer. Students reflect on the design/build process and the challenges encountered when making realistic bone replacements. A pre/post-quiz, worksheet and rubric are included. If no 3D printer, shorten the activity by just making the hand-generated replicate bones.

After learning, comparing and contrasting the steps of the engineering design process (EDP) and scientific method, students review the human skeletal system, including the major bones, bone types, bone functions and bone tissues, as well as other details about bone composition. Students then pair-read an article about bones and bone growth and compile their notes to summarize the article. Finally, students complete a homework assignment to review the major bones in the human body, preparing them for the associated activities in which they create and test prototype replacement bones with appropriate densities. Two PowerPoint(TM) presentations, pre-/post-test, handout and worksheet are provided.

Students are introduced to the respiratory system, the lungs and air. They learn about how the lungs and diaphragm work, how air pollution affects lungs and respiratory functions, some widespread respiratory problems, and how engineers help us stay healthy by designing machines and medicines that support respiratory health and function.

“Bug Hunt” uses NetLogo software and simulates an insect population that is preyed on by birds. There are six speeds of bugs from slow to fast and the bird tries to catch as many insects as possible in a certain amount of time. Students are able to see the results graphed as the average insect speed over time, the current bug population and the number of insects caught. There are two variations to try for the predator, one where the predator pursues the prey and one where the predator stays still and captures insects that pass nearby. In the first case the “bird” catches the slow insects and the faster ones survive, reproduce and pass genes on. The average speed of bug should increase over time. In the second case the faster bugs come near to the bird more often than the slow ones. The slow ones survive more, reproduce and pass their genes on.

After completing the associated lesson and its first associated activity, students are familiar with the 20 major bones in the human body knowing their locations and relative densities. When those bones break, lose their densities or are destroyed, we look to biomedical engineers to provide replacements. In this activity, student pairs are challenged to choose materials and create prototypes that could replace specific bones. They follow the steps of the engineering design process, researching, brainstorming, prototyping and testing to find bone replacement solutions. Specifically, they focus on identifying substances that when combined into a creative design might provide the same density (and thus strength and support) as their natural counterparts. After iterations to improve their designs, they present their bone alternative solutions to the rest of the class. They refer to the measured and calculated densities for fabricated human bones calculated in the previous activity, and conduct Internet research to learn the densities of given fabrication materials (or measure/calculate those densities if not found online).

This video will help students, particularly those not in AP-level classes, have a practical application for knowing about the major divisions between plants, particularly about the details of plant anatomy and reproduction. Students will be able to :Identify the major evolutionary innovations that separate plant divisions, and classify plants as belonging to one of those divisions based on phenotypic differences in plants. Classify plants by their pollen dispersal methods using pollen dispersal mapping, and justify the location of a _„ƒcrime scene_„Ž using map analysis. Analyze and present their analysis of banding patterns from DNA fingerprinting done using plants in a forensic context.

Bycatch can be defined as the act of unintentionally catching certain living creatures using fishing gear. A bycatched species is distinguished from a target species (the animal the gear is intended to catch) because it is not sold or used. Marine mammals (whales, dolphins, porpoises), seabirds, sea turtles and unwanted or undersized fish are some examples of animals caught as by-catch The incidental capture of these animals can significantly reduce their populations. The most well known example of by-catch may be the unintentional mortality of spotted and spinner dolphins in the tuna fishing industry. "Dolphin-Safe" tuna was a result of this interaction (Be prepared to discuss how this came about with students, as it is something close to their daily lives). One important aspect to consider when discussing this issue is that laws protect some of the animals caught as by-catch (Marine Mammal Protection Act and Endangered Species Act). In this lesson, students will first be shown pictures of entangled marine animals and will discuss the definition of by-catch This will lead to discussions on why by-catching exists, how it impacts specific animals as well as humans, whether the students believe it is an important issue, and how by-catch can be reduced.

In this lesson, the students look at the components of cells and their functions. The lesson focuses on the difference between prokaryotic and eukaryotic cells. Each part of the cell performs a specific function that is vital for the cell's survival. Bacteria are single-celled organisms that are very important to engineers. Engineers can use bacteria to break down toxic materials in a process called bioremediation, and they can also kill or disable harmful bacteria through disinfection.

Students color-code a schematic of a cell and its cell membrane structures. Then they complete the "Build-a-Membrane" activity found at http://learn.genetics.utah.edu. This reinforces their understanding of the structure and function of animal cells, and shows them the importance of being able to construct a tangible model of something that is otherwise difficult to see.

Students learn about the different structures that comprise cell membranes, fulfilling part of the Research and Revise stages of the legacy cycle. They view online animations of cell membrane dynamics (links provided). Then they observe three teacher demonstrations that illustrate diffusion and osmosis concepts, as well as the effect of movement through a semi-permeable membrane using Lugol's solution.

In this unit, students look at the components of cells and their functions and discover the controversy behind stem cell research. The first lesson focuses on the difference between prokaryotic and eukaryotic cells. In the second lesson, students learn about the basics of cellular respiration. They also learn about the application of cellular respiration to engineering and bioremediation. The third lesson continues students' education on cells in the human body and how (and why) engineers are involved in the research of stem cell behavior.

In this lesson, students learn about the basics of cellular respiration. They also learn about the application of cellular respiration to engineering and bioremediation. And, students are introduced to the process of bioremediation and several examples of how bioremediation is used during the cleanup of environmental contaminants.

Students teams use a laparoscopic surgical trainer to perform simple laparoscopic surgery tasks (dissections, sutures) using laparoscopic tools. Just like in the operating room, where the purpose is to perform surgery carefully and quickly to minimize patient trauma, students' surgery time and mistakes are observed and recorded to quantify their performances. They learn about the engineering component of surgery.

The topic of this video module is how to classify animals based on how closely related they are. The main learning objective is that students will learn how to make phylogenetic trees based on both physical characteristics and on DNA sequence. Students will also learn why the objective and quantitative nature of DNA sequencing is preferable when it come to classifying animals based on how closely related they are. Knowledge prerequisites to this lesson include that students have some understanding of what DNA is and that they have a familiarity with the base-pairing rules and with writing a DNA sequence.

Students are challenged to design a method for separating steel from aluminum based on magnetic properties as is frequently done in recycling operations. To complicate the challenge, the magnet used to separate the steel must be able to be switched off to allow for the recollection of the steel. Students must ultimately design, test, and present an effective electromagnet.

Students investigate decomposers and the role of decomposers in maintaining the flow of nutrients in an environment. Students also learn how engineers use decomposers to help clean up wastes in a process known as bioremediation. This lesson concludes a series of six lessons in which students use their growing understanding of various environments and the engineering design process, to design and create their own model biodome ecosystems.